Classification of Artificial Tears
Part of the
Advances in Experimental Medicine and Biology[2]
book series (AEMB, volume 438)
Abstract
Natural tears serve three main functions: they maintain the metabolism of the ocular surface tissues, afford a smooth surface that allows regular light refraction, and lubricate the ocular surface to facilitate blinking. They also have other functions, such as specific and non-specific antimicrobial and buffer effects, etc. Natural tears have a complex composition, water being the major component (98–98.5%), as well as salts, hydrocarbons, proteins, and lipids. There are two types of tear components: structural and active. The structural components of tears are rather abundant, and are the basis of the three-layered architecture of the tear film (lipid, aqueous, and mucinic) because of their physical and chemical properties. The active components of tears are very scarce, and act as nutrients, antimicrobials, enzymes, messengers, inhibitors, etc. Some tear components may serve both types of functions.
Keywords
Corneal Epithelium Lipid Layer Polyacrylic Acid Oncotic Pressure Artificial Tear
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
- 1.Swan KC. Use of methylcellulose in ophthalmology. Arch Ophthalmol. 1945; 33: 378–381.CrossRef[5]Google Scholar[6]
- 2.Aguilar Bartolomé JM. El empleb de la metilcelulosa en oftalmologia. Arch Soc Oftalmol Hisp-Amer (Arch Soc Espan Oftalmol). 1957; 17: 203–214.Google Scholar[7]
- 3.Gifford S, Puntenney I, Bellows J. Keratoconjunctivitis sicca. Arch Ophthalmol. 1943; 30: 207–216.CrossRef[8]Google Scholar[9]
- 4.Guömundsson OG, Thôrisdôttir S, Loftsson T, et al. 2-Hydroxypropyl-(3-cyclodextrin (HPPCD) and cholesterol tear substitute. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1994; 35: 5 1694.Google Scholar[10]
- 5.Cantonnet A. Formules de collyres isotoniques aux larmes. Arch Ophtalmol(Paris). 1908; 28: 617–621.Google Scholar[11]
- 6.
- 7.Gilbard JP, Kenyon KR. Tear diluents in the treatment of keratoconjunctivitis sicca. Ophthalmology. 1985; 92: 646–650.PubMed[15]Google Scholar[16]
- 8.Holly FJ, Lamberts DW. Effect of nonisotonic solutions on tear osmolarity of tear substitutes. Invest Ophthalmol Vis Sci. 1981; 20: 236–245.PubMed[17]Google Scholar[18]
- 9.Zisman WA. Relation of the equilibrium contact angle to liquid and solid constitution. ACS Adv Chem Series. 1964; 43: 1–51.CrossRef[19]Google Scholar[20]
- 10.